Nebivolol: quantum-chemical properties

1Kazakova, OA
2Dovgan, RS
2Zagorodny, MI
2Chekman, IS
1O. O. Chuiko Institute of Surface Chemistry of the NAS of Ukraine, Kyiv
2O.O. Bogomolets National Medical University, Kyiv
Dopov. Nac. akad. nauk Ukr. 2015, 12:76-82
https://doi.org/10.15407/dopovidi2015.12.076
Section: Chemistry
Language: Ukrainian
Abstract: 

Quantum-chemical properties of a molecule of β-adrenoblocator nebivolol are studied. The variety of functional groups of β-adrenoblocator nebivolol evidences about a possibility of its interaction with polar and nonpolar structures of biomembranes. An atom of nitrogen promotes the formation of a complex with β-adrenoreceptor.

Keywords: functional groups, nebivolol, quantum-chemical properties, β-adrenoblocator
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