Properties of a composite system based on fine-dispersed silica and rifampicin

1Krupskaya, TV
1O. O. Chuiko Institute of Surface Chemistry of the NAS of Ukraine, Kyiv
Dopov. Nac. akad. nauk Ukr. 2016, 4:78-85
https://doi.org/10.15407/dopovidi2016.04.078
Section: Chemistry
Language: Russian
Abstract: 

By the methods of IR and UV spectroscopy, the interaction of nanosilica particles with the antibiotic rifampicin in a wide range of its concentrations is investigated. It is shown that the optimum silica surface coverage is achieved at a rifampicin concentration of 0.4 mmol/g. The stimulating effect of the SiO2-Rif composite on the suspension of yeast cells is found. It is promising to apply the SiO2-Rif composite in the biotechnological cycles using the fermentation process with the aim to prevent the contamination of yeast cells with microorganisms.

Keywords: composite system, impregnation, nanosilica, rifampicin, yeast cells
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