Morphological and functional peculiarities of human sperm from inhabitants of radiation-polluted territories of Ukraine

TitleMorphological and functional peculiarities of human sperm from inhabitants of radiation-polluted territories of Ukraine
Publication TypeJournal Article
Year of Publication2017
AuthorsKlepko, AV, Gorban, LV, Motryna, OA, Sakovska, LV, Andreychenko, SV
Abbreviated Key TitleDopov. Nac. akad. nauk Ukr.
Date Published8/2017

Cross-sectional analysis of the sperm quality was done in 4 groups of men from Zhytomyr, Kyiv, Ivano-Frankivsk, and Poltava regions, respectively, with radiation pollution territories in the range 20-550 kBq/m2. The research has elucidated the existence of correlation links between the accumulated dose of external irradiation, on the one hand, and the growth of the index of sperm deformity, pH, and the time of sperm liquefaction, on the other hand. In addition, the sperm concentration and the progressive motility are shown to decline. The long-term residence of human males on the radiation-polluted territories has been shown to result in different sperm pathologic states, namely asthenozoospermia, oligozoospermia, and teratozoospermia.

Keywordsasthenozoospermia, oligozoospermia, radiation pollution, sperm, spermatozoa, teratozoospermia
  1. Jacquet, P. (2004). Sensitivity of germ cells and embryos to ionizing radiation. J. Biol. Regul. Homeost. Agents, 18, pp. 106-114.
  2. Fischbein, A., Zabludovsky, N. & Eltes, F. (1997). Ultramorphological sperm characteristics in the risk assessment of health effects after radiation exposure among salvage workers in Chernobyl. Environ. Health Perspect., 105, pp. 33-44.
  3. Neischlag, E., Behre, H. M. & Neischlag, S. (2010). Andrology. Male reproductive health and dysfunction, 3rd ed. Berlin, Heidelberg: Springer.
  4. Haines, G. A., Hendry, J. H., Daniel, C. P. & Morris, I. D. (2002). Germ cell and dose-dependent DNA damage measured by the comet assay in murine spermatozoa after testicular X-irradiation. Biol. Reprod., 67, pp. 854-861.
  5. WHO laboratory manual for the examination and processing of human semen, 4th ed. Cambridge: Cambridge Univ. Press, 1999.
  6. ICRP. (2007). The 2007 Recommendation of the International Commission on Radiological Protection. ICRP Publication 103. Ann ICRP, 37, No. 2-4, pp. 1-332.
  7. Moiseev, A. A. & Ivanov, V. I. (1990). Handbook of dosimetry and radiation hygiene. 4th ed. Moscow: Energoatomizdat (in Russian).
  8. Malko, M. V. (2008). Doses of the whole body irradiation in Belarus as a result of the Chernobyl accident. In Many-sided approach to the realities of the Chernobyl NPP accident (pp. 136-146), Kyoto University, Japan. KURRI-KR-21.
  9. Bland, M. (2007). An introduction to medical statistics. 3rd ed. Oxford: Oxford Univ. Press.
  10. Evdokimov, V. V., Erasova, V. I., Demin, A. I., Dubinina, E. B. & Liubchenko, P. N. (1993). State of the reproductive system of men who participated in the cleaning-up of aftereffects of the Chernobyl AES accident. Med. Tr. Prom Ekol., No. 3-4, pp. 25-26.
  11. Hoyes, K. P. & Morris, I. D. (1996). Environmental radiation and male reproduction. Int. J. Androl., 19, pp. 199-204.
  12. Tulsiani, D. R. P., Abou-Haila, A., Loeser, C. R. & Pereira, B. M. J. (1998). The biological and functional significance of the sperm acrosome and acrosomal enzymes in mammalian fertilization. Exp. Cell Res., 240, pp. 151-164.
  13. Sharma, R., Beidenharn, K. R., Fedor, J. M. & Agarwal, A. (2013). Lifestyle factors and reproductive health: taking control of your fertility. Reprod. Biol. Endocrin., 11, pp. 66-81.
  14. Wong, W. Y., Zielhius, G. A., Thomas, C. M., Merkus, H. M. & Steegers-Theunissen, R. P. (2003). New evidence of the influence of exogenous and endogenous factors on sperm count in man. Eur. J. Obstet. Gynecol. Reprod. Biol., 110, pp. 49-54.
  15. Sharp, R. M. (2000). Lifestyle and environmental contribution to male infertility. Br. Med. Bull., 56, pp. 630-642.