Influence of human placenta extracts to erythrocytes' thermohemolysis

TitleInfluence of human placenta extracts to erythrocytes' thermohemolysis
Publication TypeJournal Article
Year of Publication2018
AuthorsBobrova, OM, Govorova, Yu.S, Nardid, OA, Repina, SV, Narozhnyi, SV, Pokryshko, SV
Abbreviated Key TitleDopov. Nac. akad. nauk Ukr.
DOI10.15407/dopovidi2018.07.082
Issue7
SectionBiology
Pagination82-87
Date Published7/2018
LanguageUkrainian
Abstract

The influence of the freezing of human placenta extracts on their ability to reduce the thermohemolysis of erythrocytes has been investigated. It has been shown that the freezing of placenta extracts down to −2 and −19 °C and the following heating do not lead to a significant change in their effectiveness to stabilize the erythrocyte membranes at temperature effects. The placenta extract fractions, namely less than 4 kDa and 12—20 kDa, most effectively reducing the level of erythrocytes' thermohemolysis, have been identified. The percentages of inhibition of the thermogemolysis for them are (31.7 ± 3.3) % and (31.5 ± 3.2) %, respectively.
Keywordsantiinflammatory efficacy, erythrocytes' thermohemolysis, fraction, freezing, placenta extract
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