| Title | Aspects of the creation of neuroprotective antiinflammatory drugs |
| Publication Type | Journal Article |
| Year of Publication | 2019 |
| Authors | Chekman, IS, Belenichev, IF, Syrovaja, AO, Gorchakova, NA, Buhtijarova, NV, Ryzhenko, VP, Levashova, OL, Chalenko, NN |
| Abbreviated Key Title | Dopov. Nac. akad. nauk Ukr. |
| DOI | 10.15407/dopovidi2019.09.088 |
| Issue | 9 |
| Section | Biochemistry |
| Pagination | 88-98 |
| Date Published | 09/2019 |
| Language | Russian |
| Abstract | The chemical, physiological, and pharmacological aspects of creation of neuroprotective antiinflammatory drugs are considered. It is stated the expediency of the creation of neuroprotective compounds among the 1,2,4- tri azol derivatives and antiinflammatory compounds as the coxibes derivatives. During the synthesis of new compounds, computer programs, quantum-chemical investigations, and virtual screening have been used to determine antioxidant properties. |
| Keywords | antiinflammatory antioxidant properties, computer programs, neuroprotective, quantum- chemical investigations, virtual screening |
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