Title | Properties of pyrrol derivatives as potential anticancer compounds of a new generation |
Publication Type | Journal Article |
Year of Publication | 2014 |
Authors | Kuznietsova, HM, Lynchak, OV, Yablonska, SV, Bachurynska, OM, Danylov, MO, Bychko, AV, Rybalchenko, VK |
Abbreviated Key Title | Dopov. Nac. akad. nauk Ukr. |
DOI | 10.15407/dopovidi2014.05.138 |
Issue | 5 |
Section | Biology |
Pagination | 138-142 |
Date Published | 5/2014 |
Language | Ukrainian |
Abstract | The effects of pyrrol derivatives 5-amyno-4-(1,3-benzothyazol-2-yl)-1-(3-methoxyphenyl)-1,2-dihydro-3H-pyrrol-3-one and 1-(4-Cl-benzyl)-3-Cl-4-(CF3-phenylamino)-1H-pyrrol-2,5-dione on rat intestine and liver under 1,2-dimethylhydrazine-induced colon cancer are investigated. Low toxicity, antitumor activity, antioxidant and membranotropic properties of these compounds are observed. |
Keywords | anticancer compounds, pyrrol |
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