Properties of pyrrol derivatives as potential anticancer compounds of a new generation

TitleProperties of pyrrol derivatives as potential anticancer compounds of a new generation
Publication TypeJournal Article
Year of Publication2014
AuthorsKuznietsova, HM, Lynchak, OV, Yablonska, SV, Bachurynska, OM, Danylov, MO, Bychko, AV, Rybalchenko, VK
Abbreviated Key TitleDopov. Nac. akad. nauk Ukr.
Date Published5/2014

The effects of pyrrol derivatives 5-amyno-4-(1,3-benzothyazol-2-yl)-1-(3-methoxyphenyl)-1,2-dihydro-3H-pyrrol-3-one and 1-(4-Cl-benzyl)-3-Cl-4-(CF3-phenylamino)-1H-pyrrol-2,5-dione on rat intestine and liver under 1,2-dimethylhydrazine-induced colon cancer are investigated. Low toxicity, antitumor activity, antioxidant and membranotropic properties of these compounds are observed.

Keywordsanticancer compounds, pyrrol

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