| Title | Antimicrobial properties and toxicity of imidazolium ionic liquids and their complexes with β-cyclodextrin |
| Publication Type | Journal Article |
| Year of Publication | 2015 |
| Authors | Hodyna, DM, Kobrina, LV, Kalashnikova, LE, Metelytsia, LO, Rogalsky, SP, Tarasyuk, OP, Riabov, SV, Laptiy, SV |
| Abbreviated Key Title | Dopov. Nac. akad. nauk Ukr. |
| DOI | 10.15407/dopovidi2015.03.107 |
| Issue | 3 |
| Section | Chemistry |
| Pagination | 107-113 |
| Date Published | 3/2015 |
| Language | Ukrainian |
| Abstract | Water soluble ionic liquid 1-dodecyl-3-methylimidazolium chloride and water resistant ionic liquid 1-dodecyl-3-methylimidazolium tetrafluoroborate have been synthesized. The inclusion complexes of ionic liquids with β-cyclodextrin in a molar ratio of 1 : 1 have been obtained. The structure of the complexes was confirmed by IR-spectroscopy and differential scanning calorimetry. Antimicrobial activity of both ionic liquids and their complexes with β-cyclodextrin has been established against Staphylococcus aureus (ATCC-25923), Escherichia coli (ATCC-25922), Pseudomonas aeruginosa (ATCC-27853), Candida albicans (M 885 ATCC 10231), and Candida albicans (clinical isolate) test-cultures. It is found that the complex formation of ionic liquids with β-cyclodextrin considerably reduces their toxicity. |
| Keywords | antimicrobial properties, ionic liquids, toxicity, β-cyclodextrin |
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