Direct C-phosphorylation of 1-aryl- and 1-hetarylimidazoles by chlorides of phosphonic acids

TitleDirect C-phosphorylation of 1-aryl- and 1-hetarylimidazoles by chlorides of phosphonic acids
Publication TypeJournal Article
Year of Publication2016
AuthorsStrizhak, AV, Komarov, IV, Kornilov, MYu., Khilya, VP
Abbreviated Key TitleDopov. Nac. akad. nauk Ukr.
DOI10.15407/dopovidi2016.02.087
Issue2
SectionChemistry
Pagination87-95
Date Published2/2016
LanguageUkrainian
Abstract

A convenient efficient method for the synthesis of 1-aryl- and 1-hetarylimidazole and benzoimidazole-2-ylphosphinic acids and their derivates has been proposed. Influence of a group at position 1 of imidazole on its reactivity towards phosphonic acids chlorides is investigated. It is shown that this method provides derivates with different substituents at an aryl or hetaryl ring. This method is a good alternative to the known methods of synthesis of such compounds.

Keywordsbenzoimidazole, imidazole, phosphinamide, phosphinic acid, phosphorylation
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