Properties of a composite system based on fine-dispersed silica and rifampicin

TitleProperties of a composite system based on fine-dispersed silica and rifampicin
Publication TypeJournal Article
Year of Publication2016
AuthorsKrupskaya, TV
Abbreviated Key TitleDopov. Nac. akad. nauk Ukr.
DOI10.15407/dopovidi2016.04.078
Issue4
SectionChemistry
Pagination78-85
Date Published4/2016
LanguageRussian
Abstract

By the methods of IR and UV spectroscopy, the interaction of nanosilica particles with the antibiotic rifampicin in a wide range of its concentrations is investigated. It is shown that the optimum silica surface coverage is achieved at a rifampicin concentration of 0.4 mmol/g. The stimulating effect of the SiO2-Rif composite on the suspension of yeast cells is found. It is promising to apply the SiO2-Rif composite in the biotechnological cycles using the fermentation process with the aim to prevent the contamination of yeast cells with microorganisms.
Keywordscomposite system, impregnation, nanosilica, rifampicin, yeast cells
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