Properties of a composite system based on fine-dispersed silica and rifampicin

TitleProperties of a composite system based on fine-dispersed silica and rifampicin
Publication TypeJournal Article
Year of Publication2016
AuthorsKrupskaya, TV
Abbreviated Key TitleDopov. Nac. akad. nauk Ukr.
Date Published4/2016

By the methods of IR and UV spectroscopy, the interaction of nanosilica particles with the antibiotic rifampicin in a wide range of its concentrations is investigated. It is shown that the optimum silica surface coverage is achieved at a rifampicin concentration of 0.4 mmol/g. The stimulating effect of the SiO2-Rif composite on the suspension of yeast cells is found. It is promising to apply the SiO2-Rif composite in the biotechnological cycles using the fermentation process with the aim to prevent the contamination of yeast cells with microorganisms.

Keywordscomposite system, impregnation, nanosilica, rifampicin, yeast cells
  1. Babjeva I. P., Chernov I. Yu. Biology of yeast, Moscow: T-vo nauchn. izd. KMK, 2004 (in Russian).
  2. Magomedova E. S., Abdullabekova D. A., Abramov Sh. A. Ecology of microorganisms, 2009, No 1: 99–102 (in Russian).
  3. Ilyushkina L. N. Yeast fungi and their metabolic products, Rostov-na-Donu: YuFU, 2010 (in Russian).
  4. Industrial Microbiology, Ed. N. S. Egorov, Moscow: Vysshaya shkola, 1989 (in Russian).
  5. Burian N. I., Tyurin L. V. Microbiology of wine, Moscow: Pischevaya promyshlennost, 1979 (in Russian).
  6. Gun’ko V. M., Turov V. V., Bogatyrev V. M., Zarko V. I., Leboda R., Goncharuk E. V., Novza A. A., Turov A. V., Chuiko A. A. Adv. Colloid Interface Sci., 2005, 118: 125–172.
  7. Gun’ko V. M., Turov V. V. Nuclear Magnetic Resonance Studies of Interfacial Phenomena, New York: Taylor&Francis, 2013.
  8. Egorov N. S. Fundamentals of Theory of Antibiotics, Moscow: Izd-vo Mosk. un-ta, Nauka, 2004 (in Russian).
  9. Navashin S. M., Fomina I. P. Rational of therapy antibiotic, Moscow: Meditsina, 1982 (in Russian).
  10. Mashkovsky M. D. Drugs, Moscow: Novaya volna, 2012 (in Russian).
  11. Terenin A. N. Photonics of dye molecules and related organic compounds, Leningrad: Nauka, 1967 (in Russian).
  12. Howes B. D., Guerrini L., Sanchez-Cortes S., Marzocchi M. P., Garcia-Ramos J. V., Smulevich G. J. Raman. Spectrosc., 2007, 38: 859–864.
  13. Biçer E., Ëzdemir S. Electrochimiya, 2010, 46, No 8: 954–961 (in Russian).