Composites for prolonged release of bioactive compounds based on orchids leaves extracts and fumed silica

TitleComposites for prolonged release of bioactive compounds based on orchids leaves extracts and fumed silica
Publication TypeJournal Article
Year of Publication2019
AuthorsIvannikov, RV, Laguta, IV, Stavinskaya, ON, Anishchenko, VM, Buyun, LI, Pakhlov, EM
Abbreviated Key TitleDopov. Nac. akad. nauk Ukr.
Date Published04/2019

Bioactive extracts are prepared from leaves of the plants of Orchidaceae Juss. Their composition is investigated by the HPLC method. By means of adsorption of the extracts on fumed silica, bioactive composites were obtained. IR and UV/VIS spectroscopies are used for the characterization of composites, and the release of the extract components from the composites into water and ethanol solutions is studied. Phenolic acids and flavonoids in the glycoside form are the main groups of bioactive compounds revealed in the extracts; in the composites, these compounds appear to interact with silica silanol groups. Only a small part of the compounds is found to be released from the composites into aqueous media. The content of desorbed phenols in the ethanol solution was much higher, but the release of various components of the extracts occurred not simultaneously. The distinctions in the desorption of various phenols appoint to the different interactions of the substances with the silica surface and provide a possibility to use silica for a prolonged release of bioactive compounds.

Keywordscomposites, fumed silica, Orchidaceae Juss. extracts, phenolic compounds

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