Effect of trifluoroacetic acid on the water clustering in partially dehydrated rat liver with Guerin carcinoma

TitleEffect of trifluoroacetic acid on the water clustering in partially dehydrated rat liver with Guerin carcinoma
Publication TypeJournal Article
Year of Publication2014
AuthorsTurov, VV, Todor, IN, Lukianova, NYu., Krupskaya, TV, Ugnivenko, AP, Chekhun, VF
Abbreviated Key TitleDopov. Nac. akad. nauk Ukr.
DOI10.15407/dopovidi2014.02.129
Issue2
SectionChemistry
Pagination129-135
Date Published2/2014
LanguageUkrainian
Abstract

The state of water in lyophilized liver tissue of rats, intact and impressed by Guerin carcinoma is investigated by the method of low-temperature 1H NMR spectroscopy. It was found that six types of water clusters that can dissolve different amounts of trifluoroacetic acid are present in intact tissue. In the liver tumor, clusters SAW are more homogeneous, and their solvent abilities are significantly smaller with respect to TFA and electron-donor molecules.
KeywordsGuerin carcinoma, rat liver, trifluoroacetic acid, water clustering
References: 

1. Chekhun V. F., Mikhailenko V. M., Trindiak V. P. et al. Grade Structured Water content by NMR spectroscopy in plasma membranes Guerin carcinoma cells weekends and phenotype of resistance to doxorubicin: Proceedings of the Ukr. scientific conference with international participation “The molecular bases i Clinical rezystentnosti to problems of medicines”. Kyiv: Onkologiia: 2006, Spec. Iss.: 64 (in Ukrainian).
2. Chekhun V. F., Mikhailenko V. M., Chekhun S. V., Chalyi O. V. Dopov. Nac. akad. nauk Ukr., 2008, No. 2: 178–185 (in Ukrainian).
3. Ado A. D., Pytsky I., Poryadin G. V., Vladimirov Yu. A. (Eds.). Pathological physiology. Moscow: Triada-X, 2000 (in Russian).
4. Theriault B. L., Nachtiga M.W. Cancer Lett., 2011, 313: 108– 121. https://doi.org/10.1016/j.canlet.2011.08.033
5. Deberardinis R. J., Cheng T. Oncogene, 2010, 29, No. 3: 313–324. https://doi.org/10.1038/onc.2009.358
6. Icard P., Poulain L., Lincet H. Rev. Art. Biochim. Biophys. Acta (BBA). Rev. Cancer., 2012, 1825, Iss. 1: 111–116.
7. Turov V. V., Chehun V. F., Barvinchenko V. N. et al. J. Mater Sci, Mater Med., 2011, 22: 525–532. https://doi.org/10.1007/s10856-011-4237-3
8. Shpak A. P., Chekhun V. F. (Eds.) Nanomaterials and nanocomposites in medicine, biology, ecology. Kyiv: Nauk. dumka, 2011 (in Russian).
9. Gun’ko V. M., Turov V. V., Gorbik P. P. Water at the interface. Kyiv: Nauk. dumka, 2009 (in Russian).
10. Turov V. V., Gun’ko V. M. Clustered water and ways to use it. Kyiv: Nauk. dumka, 2011 (in Russian).
11. Gun’ko V. M., Turov V. V. Nuclear Magnetic Resonance Studies of Interfacial Phenomena. New York: Taylor & Francis, 2013. https://doi.org/10.1201/b14202
12. Turov V. V., Gun’ko V. M., Turova A. A. et al. Colloids and Surface A: Physicochem. and Eng. Asp., 2011: 48–55. https://doi.org/10.1016/j.colsurfa.2011.08.053
13. Glushko V. P. (Ed.). Thermodynamic properties of individual substances. In 4 vols. Vol. 1. Moscow: Nauka, 1978 (in Russian).